Tag Archives: model

Tissue model reveals role of blood-brain barrier in Alzheimer’s

Anne Trafton | MIT News Office Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer’s patients, disrupt many brain functions and can kill neurons. They can also damage the blood-brain barrier — the normally tight border that prevents harmful molecules in the bloodstream from entering the brain. MIT engineers have now developed… Read More »

Mass. General researchers develop 3-D ‘mini-gut’ model to study response to gluten

In pursuit of a novel tool for the research and treatment of celiac disease, scientists at the Mucosal Immunology and Biology Research Center (MIBRC) at Massachusetts General Hospital (MGH) have validated the use of intestinal organoids. These 3-D tissue cultures are miniature, simplified versions of the intestine produced in vitro. Taking tissue from duodenal biopsies of celiac… Read More »

About 1 in 5 healthcare payments is tied to value-based model

Brief Published Jan. 11, 2019 Dive Brief: Value-based care and other healthcare quality initiatives have made inroads, with an estimated 4% annual growth in value-based payments and 7% average annual increase in hospitals and clinicians participating in major clinical registries, a new Q-Centrix report shows. The consultancy’s report looks at participation in quality programs and resource… Read More »